Taking certain prescription painkillers or anxiety medications for long periods of time may increase patients’ risk of death, according to a recent Yale School of Medicine study of veterans. Researchers who examined the medical records of about 64,000 veterans found that patients who took opioids or benzodiazepines long-term, for 90 days or more, had a higher risk of death – from any cause – than those who did not. The risk of death was even greater for patients who took both types of medication at the same time. More than a quarter of the veterans studied were HIV-positive, and they had a higher risk of death than those without the virus. Opioids are painkillers that include Vicodin and Oxycontin while benzodiazepines, such as Valium, typically are prescribed to treat anxiety and insomnia.