This much we know: Boys and girls are different. We also know this: Adolescence is the most challenging time of life, and teen girls are particularly challenged to get through those years unscathed. Suicide attempts spike during the teen years, yet even with all that, it’s tough to know what’s “normal,” and what is cause for alarm. And that’s even truer for girls. By the time girls and boys hit their teen years, girls are more than twice as likely to be diagnosed with a mood disorder than are teen boys.