Observing the brain activity of preschool children with autism can help predict their response to treatment for the disorder, according to a study by Yale University researchers. The finding is groundbreaking because it can help match children with a treatment that will work for them, said Pamela Ventola, senior author of a study published today in the journal Translational Psychiatry. “We hope that we can use this information to better develop treatments for autism and better match kids with autism to a treatment that’s going to work for them,” said Ventola, an assistant professor at the Yale Child Study Center. In the study, researchers worked with 20 autistic preschoolers for 16 weeks, for seven hours each week. During sessions, children underwent pivotal response treatment, a well-established behavioral treatment for autism that dates to the 1970s and is play-based.