After Trials With Yale Researchers, FDA-Approved Treatment To Delay Type 1 Diabetes Brings Hope

The Food and Drug Administration’s recent approval of the first treatment that would delay the onset of type 1 diabetes ignited joy and hope among families impacted by the chronic, incurable disease. A clinical study found immunotherapy treatment with the drug teplizumab postponed the onset of type 1 diabetes (T1D) among at-risk children and adults for an average of two years, and for one patient, 11 years and counting. “Half the people in the study are way beyond two years,” says Yale University’s Dr. Kevan Herold, who has been working on a cure for T1D for 30 years. People with T1D have to manage the disease 24/7 or risk dangerously low or high blood sugar levels and long-term complications, said Herold, the clinical trial’s principal investigator. Before participating in a clinical trial at age 9, Claire Wirt, now 16, had antibodies that put her at risk of developing T1D within two years.

Connecticut Is Only State That Prohibits Vending-Machine Sales Of OTC Meds, Including Morning-After Pill

In Massachusetts, California, Pennsylvania and other states, students on some college campuses can purchase the “morning-after” pill from vending machines. But students in Connecticut don’t have that option because Connecticut is the only state that prohibits the sale of any over-the-counter medications in vending machines, according to the American Society for Emergency Contraceptives. The emergency contraceptive, commonly called Plan B, has been approved for purchase for those 15 and older without a prescription since 2013. Before that, a prescription was required for teenagers 17 and younger. With the U.S. Supreme Court’s overturning of Roe v. Wade in June, there’s been a flurry of activity across the country to protect reproductive rights.

Lockdowns, Remote Learning Contribute To Surge In Childhood Obesity

Poor nutrition, stress and a loss of physical activity when schools closed during the COVID-19 pandemic appear to be worsening the problem of childhood obesity nationally and in Connecticut. Nationally, obesity among youth ages 2 to 19 increased from 19.3% in 2019 to 22.4% in 2020, according to the Robert Wood Johnson Foundation. The same age group saw the rate of increase in their body mass index (BMI) double during the pandemic, the U.S. Centers for Disease Control and Prevention reports. The heaviest youths experienced the highest gains. In Connecticut, the obesity rate among ages 10 to 17 rose from 13.3% in 2018-19 to 15.3% in 2019-2020, according to the Johnson Foundation report.

Crime On CT College Campuses Drops By 29% in 2020; Pandemic Credited

New college safety data revealed a 29% decrease in all crimes reported across Connecticut’s 10 largest four-year undergraduate institutions from 2019 to 2020, including a 42% decrease in sexual offenses. This 29% decline marks the steepest drop in recent years. Between 2018 and 2019, reported crimes among the 10 largest universities decreased by 11% and sexual offenses decreased by 17%. University of Connecticut spokesperson Stephanie Reitz said that the COVID-19 pandemic, which halted the spring semester and moved classes online in March of 2020, can explain that year’s dip in crime. “The coronavirus pandemic significantly decreased the on-campus population at Storrs and the regional campuses for much of the 2020 calendar year, and the number of incidents reported during that period decreased as a result. Previous figures from 2019 and next year’s 2021 figures are expected to be more representative of a typical year,” Reitz wrote in a UConn press release.

Beyond COVID-19: Waste Testing A Vast Public Health Frontier

As scientists measure the prevalence of COVID-19 in the sludge flowing from New Haven sewage treatment plants, they’re also finding that our biological waste can tell them much more about our collective pathologies. Between March 19 and June 30, a group of scientists tested waste that had previously been used to detect COVID-19, looking for drugs and chemicals. The researchers found significant increases in three opioids, four antidepressants, and other chemicals in sludge from New Haven. The analysis, by scientists from the Connecticut Agricultural Experiment Station (CAES) and Yale University, offered the first glimpses of how the pandemic’s stay-at-home orders affected people’s behavior. It also underscored how important human waste can be as a resource for understanding public health and society’s habits.

A Surge In COVID-19 Testing Needed Before Connecticut Can Reopen Safely

Leslie Radcliffe looks ahead to the planned reopening of Connecticut’s economy beginning on May 20 with a mix of hope and anxiety. Hope, because people in her working-class Hill neighborhood in New Haven will be able to return to work, but anxiety because she’s worried that the “reopening” won’t go smoothly. In particular, she is concerned about testing for coronavirus. Will there be enough testing so the disease won’t catch fire again and threaten the lives and livelihoods in her predominantly black and Latinx neighborhood? Radcliffe, an administrative assistant at Yale University, has been working from home, but last week she began driving her brother to his job at Costco.

Blacks, Poor At Higher Risk Of Heart Disease; Overall Death Rate Falls

The death rate from heart disease plummeted nationally over several decades for all racial and ethnic groups, but the rate of decline has slowed slightly and African Americans and low-income individuals are still at a higher risk of developing the disease and dying from it, according to a report from the National Center for Health Statistics. The report isn’t surprising to Dr. Edward Schuster, medical director, Stamford Health Cardiac Rehabilitation Program.  “In the United States, there’s a lot of talk about income disparity, which is a political hotcake,” Schuster said. “But what we are seeing is a life expectancy disparity. According to a recent Journal of American Medical Association, if you’re a man in the top 1 percent of income, you can expect to live 13 years longer than someone in the 1 percent at the bottom.”

Heart disease is largely preventable by maintaining a balanced diet, a healthy weight and moderate exercise, with only 20 percent of cases involving genetics, said Dr. David L. Katz, who heads the Yale-Griffin Prevention Research Center, which works with communities to develop programs to control chronic diseases. But significant groups in lower income and urban areas don’t—or can’t—act on the message, Katz said.