Researchers at Yale University are testing whether a humorous card game can help young, black women reduce their chances of contracting HIV and AIDS—part of a new but growing trend examining whether games can spur health behavior changes. Played among three to five people, “One Night Stan” has players draw cards to establish sexual scenarios and then prompts players to discuss how they would react in those settings. The game, developed by play2PREVENT, a gaming lab within the Yale School of Medicine, is still a prototype, but designers are hoping to launch a video game version eventually and bring it to a broader audience. “It’s really about evaluating sexual situations and encounters,” said Kimberly Hieftje, a developer of the game who is an associate research scientist at Yale School of Medicine and deputy director of the play2PREVENT Lab. A growing number of developers, in Connecticut and nationally, are testing whether card, video, online and mobile games are effective tools for getting people to make healthier choices.